Lixisenatide is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist developed for the treatment of type 2 diabetes. It is a 44-amino acid peptide analog of…

Plecanatide is a synthetic, 14-amino acid peptide analog of the endogenous human hormone uroguanylin. It is designed to mimic the structure and function of uroguanylin,…

Linaclotide is a synthetic, 14-amino acid peptide analog of the endogenous hormones guanylin and uroguanylin. It was rationally designed as a potent and selective agonist…

An MC4R agonist approved for rare monogenic forms of obesity caused by leptin-melanocortin pathway defects, plus acquired hypothalamic obesity following hypothalamic injury. Marketed as Imcivree.…

Glucagon is a 29-amino acid peptide hormone that plays a critical counter-regulatory role to insulin in glucose homeostasis. It was discovered in 1923 as a…

Insulin lispro is a rapid-acting insulin analog developed to improve postprandial glycemic control in diabetes mellitus. It was the first insulin analog approved for clinical…

A synthetic amylin analog for postprandial glucose control as an adjunct to mealtime insulin in patients on intensive insulin therapy. As of the latest available…

Ziconotide is a synthetic, 25-amino acid peptide analog of ω-conotoxin MVIIA, a neurotoxic peptide originally isolated from the venom of the predatory marine cone snail…

Mazdutide (IBI362) is a novel, synthetic, long-acting peptide engineered to function as a dual agonist for the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor…

◐ Promising  |  *for obesity and metabolic dysfunction-associated steatohepatitis (MASH)*