A 16-amino-acid fragment of human growth hormone (residues 177–191) developed for obesity in the early 2000s, then abandoned at Phase 3.
Follistatin-344 is a specific isoform of follistatin, a secreted glycoprotein originally discovered in ovarian follicular fluid. It functions as a potent antagonist of activin, a…
Des(1-3)IGF-1 is a truncated analog of Insulin-like Growth Factor-I (IGF-1), a key peptide hormone structurally homologous to proinsulin and primarily produced in the liver in…
Insulin-like Growth Factor-1 Long R3 (IGF-1 LR3) is a synthetic, 83-amino acid analog of human IGF-1, a critical hormone involved in growth and development. It…
Growth Hormone-Releasing Hormone (GHRH) is a hypothalamic peptide hormone that plays a central role in the neuroendocrine regulation of growth hormone (GH) secretion from the…
Mazdutide (IBI362) is a novel, synthetic, long-acting peptide engineered to function as a dual agonist for the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor…
◐ Promising | *for obesity and metabolic dysfunction-associated steatohepatitis (MASH)*
Exenatide is a 39-amino acid peptide originally isolated from the venom of the Gila monster (Heloderma suspectum). It is a synthetic analog of exendin-4, a…
The original GLP-1 receptor agonist that opened the door for semaglutide and tirzepatide.
A porcine-brain-derived peptide preparation approved in many European, Russian, and Asian markets but not in the US.