Oxytocin
One of the oldest synthetic peptide therapies in continuous medical use — synthesized in 1953 by du Vigneaud (Nobel Prize that year), and on every…
Peptide Database
Polymyxin B
A cyclic lipopeptide antibiotic discovered in 1947, dropped from common use in the 1970s due to toxicity, and resurrected in the 2000s as one of…
Nafarelin
A synthetic GnRH agonist administered as an intranasal spray — same paradoxical-suppression mechanism as leuprolide, different delivery route.
Leuprolide
A synthetic GnRH agonist that paradoxically suppresses gonadal hormone production through receptor downregulation.
Kisspeptin
A 54-amino-acid peptide hormone (and its bioactive 10-amino-acid fragment kisspeptin-10) that sits at the apex of the reproductive endocrine axis — upstream of GnRH, regulating…
Alpha-Melanocyte-Stimulating Hormone
Alpha-Melanocyte-Stimulating Hormone (α-MSH) is a 13-amino acid endogenous neuropeptide that is a primary cleavage product of the proopiomelanocortin (POMC) precursor protein. It was first identified…
Enfuvirtide
Enfuvirtide is a 36-amino acid synthetic peptide and the first member of the class of HIV entry inhibitors, specifically a fusion inhibitor. It was developed…
FOXO4-DRI
FOXO4-DRI is a synthetic, rationally designed senolytic peptide. It was developed to selectively induce apoptosis in senescent cells, which are cells that have entered a…
Thymosin alpha-1
Thymosin alpha-1 (Tα1) is a 28-amino acid peptide fragment derived from the larger precursor protein prothymosin alpha. It was first isolated from bovine thymus tissue…
Romidepsin
Romidepsin is a potent bicyclic depsipeptide and a selective inhibitor of histone deacetylases (HDACs), specifically Class I HDACs (1, 2) and Class IIb (HDAC6). It…